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载脂蛋白 C (Apo C )是脂蛋白脂酶 (L PL)的辅助因子 ,在脂类代谢中具有重要的生物学功能。Apo C 过度表达或缺失均可导致高脂血症。本文就 Apo C 的分子结构、生物学功能、基因表达与调节及其多态性等方面的进展作一综述
Apolipoprotein C (Apo C) is a cofactor for lipoprotein lipase (LPL) and has important biological functions in lipid metabolism. Apo C overexpression or loss can lead to hyperlipidemia. This review summarizes the molecular structure, biological functions, gene expression and regulation of Apo C and its polymorphism