The effects of the modification of electrode/ceramic interfaces through a chemical solution deposition-derived PbO buffer layer on the fatigue endurance of lead zirconate titanate (PZT) thin films were investigated. The grain size and the surface roughness of the PZT films increased through PbO interfacial modification. Moreover, the PZT films with PbO interracial modification had a better crystallographic strucrare and no evident secondary phases were observed. While the remanent polarization and dielectric constant were reduced, the fatigue endurance was improved. Based on the results, the mechanism for the fatigue endurance improvement was discussed.