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选择12例不同类型的卵巢纤维上皮瘤进行临床和病理方面的比较观察,其中良性纤维上皮瘤4例;增生性纤维上皮瘤3例;恶性纤维上皮瘤2例;移行细胞癌3例。组织学上,鉴别良恶性纤维上皮瘤的关键是判断是否有间质浸润,恶性纤维上皮瘤和移行细胞癌均有间质浸润,但后者无良性或增生性纤维上皮瘤成分。2例恶性纤维上皮瘤均有增生性纤维上皮瘤成分,支持恶性纤维上皮瘤由增生性纤维上皮瘤转化而来的观点。随访结果显示:移行细胞癌预后差。我们认为区分卵巢纤维上皮瘤的类型和分化程度对指导临床治疗和判断病人预后具有重要意义。
12 cases of different types of ovarian fibroepithelioma were selected for clinical and pathological comparison, including 4 cases of benign fibrous epithelioma, 3 cases of proliferative fibrous epithelial tumor, 2 cases of malignant fibrous epithelial tumor and 3 cases of transitional cell carcinoma. Histologically, the key to identify benign and malignant fibrous epithelioma is to determine whether there is interstitial infiltration, malignant fibrous epithelial tumor and transitional cell carcinoma are interstitial infiltration, but the latter non-benign or proliferative fibrous epithelial tumor components. 2 cases of malignant fibrous epithelial tumors have proliferative fibrous epithelial tumor components, supporting the malignant fibrous epithelioma transformed by the proliferation of fibrous epithelial tumors from the point of view. Follow-up results show: poor prognosis of transitional cell carcinoma. We think that distinguishing the type and degree of differentiation of ovarian fibroepithelioma is of great significance for guiding the clinical treatment and judging the prognosis of patients.