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本文报导马拉松赛跑后发生肌红蛋白尿合并急性肾功能衰竭1例。病人男,20岁,家族及本人无肌疾患史。因马拉松赛跑后出现两大腿无力,意识障碍,急症入院。入院时体温39.1℃,脉搏130～150/分,多汗、烦渴,两腿伸侧肌痛,有压痛。尿呈深褐色、浑浊,尿沉渣可见白细胞、红细胞、上皮及颗粒管型;GOT、GPT、LDH,CPK升高,钾与磷降低,次日脉搏、体温正常;肌痛1周后消失;褐色尿3～4天消失,出现急性肾功能衰竭。第7天GOT683单位、GPT179单位,LDH3904单位,可见LDH_5,以后逐渐正常。第9天血尿素氮136毫克％,肌酸酐19.3毫克％,钾6.3毫当量/升,行腹膜透析。第13天血尿素氮164毫克％、肌酸酐19.4毫克％,钾透析后降低,第27天正常;尿量从第18天增加,40天后恢复正
This article reports a case of myoglobinuria with acute renal failure after marathon race. Male patient, 20 years old, family history of myasthenic disease. Due to marathon after two thighs appear weakness, unconsciousness, emergency admission. Admission temperature 39.1 ℃, pulse 130 ~ 150 / points, sweating, polydipsia, legs, lateral muscle pain, tenderness. Urine dark brown, turbid, urine sediment visible white blood cells, red blood cells, epithelial and granular tube type; GOT, GPT, LDH, CPK increased potassium and phosphorus decreased pulse the next day, body temperature normal; disappeared after 1 week of myalgia; brown Urine 3 to 4 days disappeared, acute renal failure. Day 7 GOT683 units, GPT179 units, LDH3904 units, visible LDH_5, gradually normal after. The first nine days of blood urea nitrogen 136 mg%, creatinine 19.3 mg%, potassium 6.3 meq / l peritoneal dialysis. Blood urea nitrogen 164 mg%, creatinine 19.4 mg%, potassium decreased after dialysis on day 13, normal on day 27; urine output increased from day 18 and recovered after 40 days