卵巢始基卵泡的耗竭,伴随着生殖功能的丧失,一般发生于45～55岁之间,若一个有正常初潮及规则月经的妇女,而在30岁以前绝经,则谓之早期绝经(Premature menopause),或称早期卵巢功能衰竭(Premature ovarian failure)。其特征是持续性闭经;促性腺激素水平升高;雌激素水平低落,与绝经后妇女相同。早期绝经虽 Ovarian primordial follicle depletion, with the loss of reproductive function, usually occurs between 45 and 55 years old. If a woman with normal menarche and regular menstruation, and menopause before the age of 30, then the premature menopause ), Or premature ovarian failure. It is characterized by persistent amenorrhea; elevated levels of gonadotropins; low estrogen levels, as in postmenopausal women. Although the early menopause