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目的观察虫草多糖体外对佐剂性关节炎大鼠免疫功能的影响。方法采用佐剂性关节炎大鼠（AA）的免疫细胞体外给药培养并检测一些免疫指标（ConA增殖反应、IL-1、IL-2）。结果虫草多糖（10、100mg·L－1）既对AA大鼠过低的ConA增殖反应有明显的促进作用，又对AA大鼠低下的IL－2产生有明显的促进作用。但5个浓度（0．01、0．1、1、10、100mg·L-1）对AA大鼠过高的IL-1产生无明显影响。结论虫草多糖可能具有免疫增强作用。
Objective To observe the effect of Cordyceps polysaccharide on the immune function of adjuvant arthritis rats in vitro. Methods The immune cells of adjuvant arthritis rats (AA) were used to culture and detect some immune parameters (ConA proliferation, IL-1, IL-2). Results Cordyceps polysaccharide (10, 100 mg·L-1) not only promoted the proliferation of ConA in AA rats, but also promoted the production of IL-2 in AA rats. However, 5 concentrations (0.01, 0.1, 1, 10, 100 mg·L-1) had no significant effect on IL-1 production in AA rats. Conclusion Cordyceps polysaccharide may have immune enhancement.