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目前,人们对血清唾液酸浓度和心血管病死亡的确切关系、纤维蛋白原是否是解释二者关系的影响因素等问题的认识均不清楚。所以。作者研究了血清唾液酸浓度与各种止血因子血浆浓度以及吸烟影响的关系。对象与方法研究对象为每年进行健康检查的60岁以上138名日本健康男性。取清晨空腹血为样本,测其血清唾液酸、总胆固醇和甘油三磷酸氧化酶浓度,血浆纤维蛋白原和因子Ⅶ的凝血活性,抗凝血酶Ⅲ、肝素副因子Ⅱ、纤维蛋白溶酶原和α_2-纤维蛋白溶酶抑制因子的血浆浓度以及α-脂蛋白、因子Ⅶ
At present, people’s understanding of the exact relationship between serum sialic acid concentration and death of cardiovascular diseases, and whether fibrinogen is the influencing factor in the relationship between the two are unclear. and so. The authors studied the relationship between serum sialic acid concentrations and various hemostatic plasma concentrations and the effects of smoking. Subjects and Methods Subjects were 138 healthy Japanese men over the age of 60 who underwent an annual medical examination. Fasting blood samples taken early morning, measured serum sialic acid, total cholesterol and triglyceride oxidase concentration, plasma fibrinogen and factor Ⅶ coagulation activity, antithrombin Ⅲ, heparin factor Ⅱ, plasminogen And plasma concentrations of α_2-plasmin inhibitor as well as plasma levels of α-lipoprotein, factor Ⅶ