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目的:观察用白眉蛇毒血凝酶(邦亭)治疗上消化道出血的疗效。方法上消化道出血患者90例,随机分为治疗组和对照组,所有病例均给予扩容及调整水电解质紊乱,静滴奥美拉唑42.6 mg,每日1次;静滴卡络磺钠60 mg,每日1次,重度贫血者予输血。治疗组再应用邦亭4 KU加生理盐水20 mL口服,每日2次,对照组用去甲肾上腺素8 mg加生理盐水90 mL,每日分3次口服。结果治疗组总有效率93.75%,对照组总有效率80.95%,两组临床疗效差异有统计学意义(P<0.05)结论:白眉蛇毒血凝酶是一种有效的、安全的治疗上消化道出血的药物,在临床止血治疗中值得推广应用。
Objective: To observe the curative effect of treating upper gastrointestinal bleeding with white eyebrow venom hemagglutinin (Bun Ting). Methods 90 patients with upper gastrointestinal bleeding were randomly divided into treatment group and control group. All cases were given dilatation and adjustment of electrolyte imbalance, intravenous omeprazole 42.6 mg once daily and intravenous infusion of sodium sulfonamide 60 mg, once daily, severe anemia were transfused. The treatment group and then apply Banting 4 KU plus saline 20 mL orally, 2 times a day, the control group with norepinephrine 8 mg plus normal saline 90 mL, 3 times a day orally. Results The total effective rate was 93.75% in the treatment group and 80.95% in the control group. There was significant difference between the two groups in clinical efficacy (P <0.05). Conclusion: The white-browed snake venom hemagglutinin is an effective and safe treatment for the upper gastrointestinal tract Bleeding drugs, in the clinical treatment of bleeding worth promoting application.