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乳腺癌除手术切除外,迄今尚无满意的治疗措施,但手术根治切除率低。自杀基因(suicidegene)疗法的出现,为乳腺癌的治疗提供了一种较为有效和具有临床应用潜力的治疗策略。本文就自杀基因治疗乳腺癌的研究进展作一综述。1自杀基因疗法的机制1.1直接杀伤作用即转染了前药转换酶基
In addition to surgical resection of breast cancer, so far there is no satisfactory treatment, but the rate of radical cystectomy is low. The emergence of suicide gene therapy has provided a more effective and clinically useful therapeutic strategy for the treatment of breast cancer. This article reviews the progress of suicide gene therapy for breast cancer. A mechanism of suicide gene therapy 1.1 direct killing effect that is transfected prodrug-converting enzyme