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目的 了解术前腹腔动脉灌注化疗对贲门癌切除术预后的影响。方法 采用随机分组的方法把手术治疗的86 例贲门癌患者分为两组,术前腹腔动脉灌注化疗后行手术治疗组42 例;单纯手术治疗组44 例。术前化疗方法为经股动脉插管至腹腔动脉,注入5 F U 1.0 g、 D D P100 m g、 M M C 20 m g。结果 术前腹腔动脉灌注化疗组术后3 年生存率为52.4% ,5 年生存率为 35.7% ,高于单纯手术治疗组术后3 年生存率 31.8% 、5 年生存率20.4% 。两组比较有统计学差异( P< 0.05)。结论、术前腹腔动脉灌注化疗能够提高贲门癌患者的术后远期生存率。
Objective To understand the effect of preoperative celiac arterial infusion chemotherapy on the prognosis of cardiac cancer resection. Methods A total of 86 cases of cardiac cancer patients undergoing surgery were randomly divided into two groups. Intra-abdominal arterial infusion chemotherapy followed by surgery was performed in 42 patients and in the surgically-only group in 44 patients. The preoperative chemotherapy was to insert the femoral artery into the celiac artery and inject 5 F U 1.0 g, D D P 100 m g, and M M C 20 m g. Results The preoperative three-year survival rate was 52.4% in the celiac arterial infusion chemotherapy group, and the 5-year survival rate was 35.7%. It was higher than the 3-year survival rate of 31.8% and 5 years survival in the surgery-only group. The rate is 20.4%. There was a statistically significant difference between the two groups (P < 0.05). Conclusions Preoperative celiac arterial infusion chemotherapy can improve postoperative survival in patients with cardiac cancer.