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辅助性T细胞17(Th17)是一种新型辅助 T细胞亚群,主要表达白细胞介素17等效应因子,已证实其在自身免疫性疾病中发挥重要的调节作用。随着研究的深入,人们发现 Th17细胞及其细胞因子亦参与了包括弥漫性毒性甲状腺肿、慢性淋巴细胞性甲状腺炎和甲状腺相关眼病在内的自身免疫性甲状腺疾病( AITD)的发病过程。该文就Th17细胞及其细胞因子在AITD发病中的作用研究进展予以综述。“,”The T helper cells 17(Th17) are a novel helper T cell subset,with interleukin 17(IL-17) as main expression ,have been proved to play an important regulatory role in the development of autoimmune dis-eases.Th17 cells may also contribute to the pathogenesis of autoimmune thyroid disorders(AITD) including diffuse toxic goiter disease,chronic lymphocytic thyroiditis,and thyroid-associated ophthalmopathy.Here is to make a review of the current knowledge regarding IL-17 and Th17 cells roles in the pathogenesis of AITD.