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目的 :‘对利用吡柔比星 (THP)作膀胱内灌注预防浅表性膀胱癌术后复发的疗效进行总结评价。方法 :2 8例浅表性膀胱癌患者行膀胱部分切除术或经尿道膀胱肿瘤电切术 ,术后 1周始定期用 THP(3 0 mg/ 4 0 m L)作 4 0 min多体位膀胱内灌注。每周 1次共 4次。其后每 2周 1次共 4次 ,以后每月 1次共 1a。结果 :经 1a随访 ,肿瘤复发 2例 ,复发率 7.6% ,仅 4例出现轻微局部反应。结论 :THP膀胱内灌注预防浅表性膀胱癌术后复发的疗效满意 ,复发率低 ,副作用轻 ,值得推广。
Objective: To evaluate the efficacy of intravesical instillation of pirarubicin (THP) in the prevention of postoperative recurrence of superficial bladder cancer. METHODS: Twenty-eight patients with superficial bladder cancer underwent partial or partial resection of bladder tumor. One week after operation, THP (30 mg / 40 m L) Internal perfusion. A total of 4 times a week. After every 2 weeks thereafter a total of 4 times a month after a total of 1 a. Results: After 1 year follow-up, the tumor recurred in 2 cases and the recurrence rate was 7.6%. Only 4 cases showed slight local reaction. Conclusion: Intravesical instillation of THP can prevent postoperative recurrence of superficial bladder cancer with satisfactory curative effect, low recurrence rate and light side effects. It is worth promoting.