人脑胶质瘤约占颅内肿瘤的半数。由于生长部位特殊，手术难于完全切除，且放疗及化疗效果不佳，因而在基因水平研究其发病机制，探讨新的诊断及治疗方法具有重要的意义。近年来，对许多与胶质瘤生成相关的原癌基因、抑癌基因、生长因子及其受体等分子标志方面的研究，揭示了胶 Human gliomas account for about half of intracranial tumors. Due to the special growth site, it is difficult to completely remove the operation, and radiotherapy and chemotherapy ineffective, so the study of its pathogenesis at the gene level, to explore new diagnostic and therapeutic methods is of great significance. In recent years, many of the glioma-related proto-oncogene, tumor suppressor genes, growth factors and their receptors and other molecular markers, revealing the plastic