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目的通过对呼吸道感染患儿的血清Ig M测定,了解郑州地区小儿9项呼吸道病原体感染情况。方法采用间接免疫荧光法,对285例呼吸道感染患儿的9种病原体Ig M抗体同时进行检测。结果 285例患儿中检出Ig M抗体阳性183例,阳性率为64.3%。其中肺炎支原体101例,占35.4%;乙型流感病毒45例,占15.8%;副流感病毒(1型、2型、3型)27例,占9.5%;腺病毒7例,占2.5%;肺炎支原体和乙型流感病毒混合感染29例,占10.2%;肺炎支原体和副流感病毒(1型、2型、3型)混合感染17例,占6.0%;肺炎支原体和腺病毒混合感染4例,占1.4%;肺炎支原体和呼吸道合胞病毒,肺炎支原体、腺病毒和副流感病毒(1型、2型、3型),肺炎支原体、甲型流感病毒和乙型流感病毒,肺炎支原体、乙型流感病毒和副流感病毒(1型、2型、3型)混合感染各1例,占0.4%。结论肺炎支原体和乙型流感病毒是本地区小儿呼吸道感染的主要病原体,且肺炎支原体易与其他病原体混合感染。
Objective To investigate the serum IgM in children with respiratory tract infection and to understand the infection status of 9 respiratory pathogens in children in Zhengzhou area. Methods The indirect immunofluorescence method was used to detect the IgM antibodies of 9 pathogens in 285 children with respiratory tract infection simultaneously. Results Among the 285 cases, 183 positive IgM antibodies were detected, the positive rate was 64.3%. Among them, 101 cases were Mycoplasma pneumoniae, accounting for 35.4%; 45 cases were Type B influenza virus, accounting for 15.8%; 27 cases were parainfluenza virus (Type 1, Type 2 and Type 3), accounting for 9.5%; 7 cases were adenovirus, accounting for 2.5% Mycoplasma pneumonia and influenza B virus infection in 29 cases, accounting for 10.2%; Mycoplasma pneumoniae and parainfluenza virus (type 1, type 2, type 3) mixed infection in 17 cases, accounting for 6.0%; Mycoplasma pneumoniae and adenovirus mixed infection in 4 cases , Accounting for 1.4%; Mycoplasma pneumoniae and respiratory syncytial virus, Mycoplasma pneumoniae, adenovirus and parainfluenza virus (type 1, type 2, type 3), Mycoplasma pneumoniae, influenza A and B, Mycoplasma pneumoniae, Influenza virus and parainfluenza virus (type 1, type 2, type 3) mixed infection in 1 case, accounting for 0.4%. Conclusions Mycoplasma pneumoniae and influenza B virus are the main pathogens of respiratory tract infection in children in this area. Mycoplasma pneumoniae is easily mixed with other pathogens.