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目的探讨地西泮与山莨菪碱在缩短中孕引产产程、降低第二次引产和中孕取胎机会,减轻患者痛苦的作用。方法本研究选择自2004年5月至2008年5月,在本院中孕引产妇女用药时间超过48h,不规律性宫缩超过14h者共133例为研究对象,按照随机设立对照组和实验组。实验组76例给予联合使用地西泮与山莨菪碱,对照组67例给予生理盐水作安慰剂。结果用药后6h内引产成功率:试验组为80.26%,对照组仅为17.92%,结果有显著性差异(P<0.01);而两组出血超过300ml者均为3例,无显著性差异;试验组的疼痛指标平均为5.11,显著低于对照组6.72(P<0.05)。结论对于中孕引产者联合使用地西泮和山莨菪碱能够明显缩短产程,提高引产成功率,减轻疼痛。
Objective To investigate the effect of diazepam and anisodamine on shortening labor induction during second trimester and the chances of second trimester and second trimester fetus and lessening the pain of patients. Methods The study selected from May 2004 to May 2008, in our hospital induced abortion women medication more than 48h, irregular contractions more than 14h were a total of 133 cases, according to the random set up a control group and experimental group . In the experimental group, 76 cases were given diazepam and anisodamine, while 67 cases in the control group were given saline as placebo. Results The success rate of induction of labor within 6 hours after treatment was 80.26% in the test group and 17.92% in the control group, with significant difference (P <0.01). However, no significant difference was found between the two groups of more than 300ml, The pain index of the experimental group averaged 5.11, which was significantly lower than that of the control group 6.72 (P <0.05). Conclusions The use of diazepam and anisodamine in the induction of labor in middle pregnancy can significantly shorten the labor process, improve the success rate of induced labor and relieve the pain.