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目的:了解本地区新生儿病毒及支原体肺炎的病原学分布。方法:采用免疫酶法(ELISA)检测肺炎患儿血中8型常见病毒及支原体特异性 IgM。结果:肺炎组111份血清中,特异性 IgM 检测阳性40份(36.04%);对照组30份血清检测均阴性。40份阳性血清中,8型病毒及支原体 IgM 检测阳性50例次,其中 RSV1例(0.9%),ADV_317例(15.3%),ADV_71例(0.9%),PIV4例(3.6%),CoxB5例(4.5%),ECHO10例(9.0%),CMV7例(6.3%),MP5例(4.5%),HSV_1未检出;33份(29.7%)检测出1种特异性 IgM,7份(6.3%)检测出2种或2种以上特异性 IgM。结论:病毒及支原体为本地区新生儿肺炎的重要病原,南方的病原学分布与北方不同,多种病原可混合感染。
Objectives: To understand the etiology of neonatal and mycoplasmal pneumonia in this region. Methods: Eight types of common viruses and mycoplasma-specific IgM in blood of children with pneumonia were detected by enzyme-linked immunosorbent assay (ELISA). Results: Among the 111 sera of pneumonia group, 40 (36.04%) were positive for specific IgM and 30 were negative for control group. Of the 40 positive samples, 50 were positive for type 8 virus and mycoplasma IgM, RSV1 (0.9%), ADV317 (15.3%), ADV71 (0.9%), PIV4 (3.6%) and CoxB5 4.5%), 10 cases of ECHO (9.0%), 7 cases of CMV (6.3%), MP5 cases (4.5%) and HSV_1 were not detected. Two or more specific IgMs were detected. Conclusion: Mycoplasma and Mycoplasma are the important pathogens of neonatal pneumonia in the region. The etiology of the south is different from that of the north and many pathogens can be mixed and infected.