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结核杆菌耐药是影响结核病疗效的主要因素之一。根据《中国结核病防治规划实施工作指南》要求,复治患者在未获得抗结核药药敏结果前,只能使用标准复治化疗方案[1],但其中对耐药患者却可能实施了不合理的治疗。我们对2000-2011年北京市西城区结核病防治所登记管理的复治菌阳肺结核患者的药物敏感试验结果及治疗转归进行回顾性分析,评价标准复治方案对复治菌阳患者的疗效,为制定合理的复治肺结核患者化疗方案提供依据,报告如下。
Mycobacterium tuberculosis drug resistance is one of the main factors affecting the efficacy of tuberculosis. According to the requirements of the Guidelines for the Implementation of the Program for the Prevention and Control of Tuberculosis in China, retreatment patients can only use standard chemotherapy regimens before obtaining anti-tuberculosis drug susceptibility results [1], but unreasonable ones may be implemented in those patients who are resistant Treatment. We retrospectively analyzed the drug-susceptibility test results and treatment outcome of patients with retreatment positive pulmonary tuberculosis registered and managed by the Tuberculosis Prevention and Control Center of Xicheng District in Beijing from 2000 to 2011 and evaluated the curative effect of the standard rehabilitation program on patients with retreatment bacilli, To provide a reasonable basis for the development of chemotherapy regimen in patients with pulmonary tuberculosis, the report is as follows.