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Toll样受体(TLRs)是近几年发现的天然免疫受体,它们能特异性地识别病原微生物的结构成分,激活天然免疫。目前已克隆鉴定出13种TLR,其中TLR1~10在胎盘中有表达,表明TLRs在胎盘的先天性免疫过程中可能起重要作用。
Toll-like receptors (TLRs) are innate immune receptors found in recent years. They specifically recognize the structural components of pathogenic microorganisms and activate innate immunity. Thirteen TLRs have been identified and cloned, of which TLR1 ~ 10 are expressed in the placenta, indicating that TLRs may play an important role in the placental innate immunity.