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目的:观察比较预先注入氯诺昔康对全身麻醉下行骨科手术的患儿苏醒期躁动反应。方法:骨科手术小儿60例,随机分为;2组Ⅰ组给予生理盐水2ml,Ⅱ组给予氯诺昔康1mg/kg,各30例。观察躁动评分;观察2组小儿术后有无心律失常、呼吸抑制、凝血功能异常及恶心呕吐、皮肤瘙痒等不良反应。结果:各时间点躁动评分:Ⅰ组明显高于Ⅱ组(P<0.01)。各时间点2组均无心律失常、呼吸抑制、凝血功能异常发生,恶心、呕吐、瘙痒不良反应,2组之间差异无显著性意义(P>0.05)。结论:超前静脉滴注氯诺昔康可以减少术后疼痛和苏醒期躁动,无明显不良反应,可安全用于小儿骨科手术。
OBJECTIVE: To observe and compare the effects of lornoxicam on wakefulness and recovery during general anesthesia in orthopedic surgery. Methods: Sixty children with orthopedic surgery were randomly divided into two groups: group Ⅰ was given 2 ml saline; group Ⅱ was given lornoxicam 1 mg / kg, each group was 30 cases. Observed agitation score; observed 2 groups of children with or without arrhythmia, respiratory depression, coagulation dysfunction and nausea and vomiting, skin itching and other adverse reactions. Results: The restlessness score at each time point was significantly higher in group Ⅰ than in group Ⅱ (P <0.01). There was no arrhythmia, respiratory depression, coagulation dysfunction, nausea, vomiting and pruritus adverse reactions in both groups at any time point. There was no significant difference between the two groups (P> 0.05). Conclusion: Anterior venous infusion of lornoxicam can reduce postoperative pain and wakefulness agitation, no obvious adverse reactions, safe for pediatric orthopedic surgery.