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Toll样受体(TLRs)是一组天然免疫模式识别受体。其通过启动细胞信号传导途径,激活机体的免疫细胞,触发先天性免疫应答,并对Th1/Th2型获得性免疫的成功诱导起决定性作用。现介绍TLRs在机体免疫应答及哮喘等呼吸道疾病中的免疫调节作用。
Toll-like receptors (TLRs) are a group of innate immune pattern recognition receptors. It triggers an innate immune response by activating cellular signaling pathways, activating the body’s immune cells and decisive for the successful induction of Th1 / Th2 adaptive immunity. Are described TLRs immune response in the body and asthma and other respiratory diseases in immune regulation.