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以ＮＡＤＨ－高铁氰化钾还原酶法对Ｇｒａｖｅｓ病和正常甲状腺ＮＡＤＨ－细胞色素ｂ_５还原酶（ｂ_５Ｒ）及过氧化氢酶活性进行测定。发现Ｇｒａｖｅｓ病时甲状腺的ｂ_５Ｒ活性明显增高，而过氧化氢酶活性无改变；Ｇｒａｖｅｓ病患者甲状腺ｂ_５Ｒ活性与其治前血中甲状腺激素水平呈显著正相关。表明Ｇｒａｖｅｓ病时甲状腺内产生过氧化氢酶系活性增高，可能是其甲状腺激素合成增多的重要环节。
The activities of NADH-cytochrome b_5 reductase (b_5R) and catalase in Graves’ disease and normal thyroid gland were determined by NADH-ferricyanide reductase method. Found Graves disease thyroid b_5R activity was significantly increased, and catalase activity was unchanged; Graves disease thyroid b_5R activity and its pre-treatment of thyroid hormone levels were positively correlated. That Graves disease thyroid production of catalase activity increased, may be an important part of the increase in thyroid hormone synthesis.