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目的观察分析米非司酮联合中药周期治疗子宫肌瘤的临床疗效。方法将88例确诊的子宫肌瘤患者随机分为米非司酮联合中药周期治疗组(治疗组)48例与米非司酮治疗组(对照组)40例。对照组患者服用米非司酮片12.5 mg,每天1次;治疗组每天1次服用米非司酮片12.5 mg基础上,结合患者月经周期及其证候,给予中药复方口服治疗。治疗3个月后,检测两组患者治疗前后的子宫、子宫肌瘤体积和体内激素水平。结果两组患者治疗后子宫、子宫肌瘤体积和血清激素水平均有改善,与治疗前比较,差异均有统计学意义(P<0.05)。治疗后组间比较,治疗组优于对照组,差异有统计学意义(P<0.05)。结论米非司酮联合中药周期治疗子宫肌瘤患者临床效确切。
Objective To observe the clinical efficacy of mifepristone combined with traditional Chinese medicine in the treatment of uterine fibroids. Methods 88 cases of diagnosed uterine fibroids were randomly divided into mifepristone combined with traditional Chinese medicine cyclical treatment group (treatment group) 48 cases and mifepristone treatment group (control group) 40 cases. Control group patients taking mifepristone tablets 12.5 mg once daily; treatment group taking mifepristone tablets 12.5 mg daily basis, combined with the patient’s menstrual cycle and its syndrome, given oral treatment of traditional Chinese medicine compound. After 3 months of treatment, the uterus, uterine fibroids and hormone levels in both groups before and after treatment were measured. Results The volume of uterine fibroids, uterine fibroids and serum hormone levels in both groups were improved after treatment, with statistical significance (P <0.05). After treatment, the treatment group was better than the control group, the difference was statistically significant (P <0.05). Conclusion Mifepristone combined with traditional Chinese medicine cyclical treatment of uterine fibroids in patients with exact clinical efficacy.