论文部分内容阅读
目的 探讨肌钙蛋白T和I对急性心肌梗死的诊断价值。方法 对 41例AMI、3 8例AP患者及 40例健康人分别进行血清CTnT、CTnI心肌酶学 (CK、CK -MB、AST、LDH、HBDH)测定 ,比较各指标在AMI中的诊断价值。结果 AMI病人血清CTnT、CTnI均显著高于对照组和AP组 ,阳性率分别是 95 15 %和 97 6% ,AP组的阳性率分别是 11 2 %和 7 9% ,两组间比较有显著性差异。CTnT、CTnI用于诊断AMI的各项指标均优于心肌酶。结论 肌钙蛋白T和I是诊断AMI敏感性、特异性均较好的生化指标 ,动态观察肌钙蛋白的变化对AMI诊断、判别心肌损伤程度、鉴别AMI和心绞痛具有重要的临床价值。
Objective To investigate the diagnostic value of troponin T and I in acute myocardial infarction. Methods Serum CTnT and CTnI myocardial enzymes (CK, CK-MB, AST, LDH, HBDH) were measured in 41 patients with AMI, 38 patients with AP and 40 healthy individuals. The diagnostic value of each index in AMI was compared. Results The serum levels of CTnT and CTnI in AMI patients were significantly higher than those in control group and AP group. The positive rates were 95 15% and 97 6% respectively. The positive rates in AP group were 112% and 79% respectively. There was significant difference between the two groups Sex differences. CTnT, CTnI for the diagnosis of AMI indicators are better than myocardial enzymes. Conclusions Troponin T and I are biochemical indicators of sensitivity and specificity in the diagnosis of AMI. To dynamically observe the changes of troponin has important clinical value in diagnosing AMI, judging the degree of myocardial injury, differentiating AMI and angina pectoris.