论文部分内容阅读
目的观察前列地尔联合小剂量多巴胺治疗慢性肾功能不全的临床疗效。方法将我院2010年7月至2013年5月收治的80例慢性肾功能不全患者分为观察组（n =40）和对照组（n =40），观察组患者在一般常规治疗基础上加用前列地尔联合小剂量多巴胺治疗，对照组患者给予一般常规治疗。结果观察组的疗效显著地优于对照组( P<0.05)，并且观察组的24h尿蛋白量、内生肌酐清除率、血肌酐和尿素氮都显著地优于对照组( P<0.05)。结论前列地尔联合小剂量多巴胺治疗慢性肾功能不全的疗效确切，能延缓疾病进展，值得临床推广。“,”Objective: To observe the curative effect of the alprostadil combined with low-dose dopamine for treatment of chronic renal insufficiency. Methods: 80 patients with chronic renal insufficiency in our hospital from July 2010 to May 2013 were divided into observation group (n = 40) and control group (n = 40). Observation group was given low-dose dopamine combined with alprostadil on the basis of general treatment therapy and control group was given general treatment therapy. Results: The curative effect in the observation group was significant better than that in the control group (P < 0.05). Moreover, the 24 h urine protein quantity, endogenous creatinine clearancerate, serum creatinine, and blood urea nitrogen in the observation group were significant better than those in the control group (P < 0.05). Conclusions: The alprostadil combined with low-dose dopamine for treatment of chronic renal insufficiency is efficacy, decrease in development. It is worthy to be popularized.