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目的 通过中、晚期肺癌患者的支气管动脉灌注(BAI)介入治疗的研究,探讨该方法的临床应用价值。方法 选择中、晚期肺癌患者24例。采用Seldinger技术,经股动脉穿刺插管,超选至相应支气管动脉造影。重点观察肿瘤的供血情况,注意是否存在支气管动脉与脊髓动脉共干现象,并进行支气管动脉内灌注化疗。结果 24例病人BAI介入治疗后,临床症状均缓解。CT及胸部正侧位像均显示瘤体缩小、肿瘤边缘模糊、不张的肺叶复张。2例病人行BAI2次后肿块消失,1例病人行BAI2次后手术切除。术后发热者5例,恶心、呕吐者4例。仅1例出现轻度脊髓损伤。结论 中、晚期肺癌患者的BAI疗效明显,副作用小,已经成为非手术适应症肺癌患者的主要治疗方法。
Objective To investigate the clinical value of this approach through the interventional therapy of bronchial artery infusion (BAI) in patients with advanced lung cancer. Methods Select 24 cases of advanced lung cancer patients. Using Seldinger technology, the femoral artery puncture intubation, ultrasound to the corresponding bronchial artery angiography. Focus on the observation of tumor blood supply, pay attention to the existence of bronchial artery and spinal artery co-dry phenomenon, and bronchial artery infusion chemotherapy. Results The clinical symptoms of 24 patients after BAI intervention were relieved. CT and chest are lateral images are shown tumor shrinkage, tumor edge fuzzy, atelectasis of lung reexpansion. Two patients disappeared after BAI 2 times, and one patient underwent surgical resection after BAI 2 times. Postoperative fever in 5 cases, nausea, vomiting in 4 cases. Only 1 case had mild spinal cord injury. Conclusions The efficacy of BAI in patients with advanced lung cancer is obvious and the side effects are small. It has become the main treatment for patients with non-surgical indications of lung cancer.