维持机体组织的自身稳定 ,不仅取决于正常的免疫调节及细胞增殖、分化的有序调控 ,亦有赖于细胞死亡功能的正常协调。细胞凋亡是细胞主动参与的自杀性死亡 ,不同于坏死 ,在维持机体平衡状态方面有重要的生物学意义。肿瘤的发生 ,不仅与增殖和分化异常有关 ,也与细胞凋亡异常有 Maintaining the self-stability of the body tissue depends not only on normal immune regulation and cell proliferation and orderly regulation of differentiation, but also on the normal coordination of cell death functions. Apoptosis is a suicidal death in which cells actively participate. Unlike necrosis, there is an important biological significance in maintaining body balance. Tumor occurrence, not only with the proliferation and differentiation abnormalities, but also with abnormal apoptosis