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目的:探讨儿童过敏性紫癜(HSP)复发的相关临床因素。方法:回顾性分析2010年1月至2013年12月江门市中心医院收治的118例HSP患儿的临床资料,随访1年后将患者分为无复发组和复发组,分析两组发病年龄、性别、前驱感染、过敏原阳性、Ig A升高、重症病例、1周内发现尿常规异常、开始治疗时间及敏性紫癜的发病类型等临床指标的差异。结果:过敏性紫癜复发率为29.66%,复发时间均在治疗后6个月内,前驱感染、开始治疗时间及过敏性紫癜的发病类型与复发无关(P>0.05);而两组发病年龄、性别、过敏原阳性、Ig A升高、重症病例及1周内发现尿常规异常比较,差异有统计学意义(P<0.05),其中重症病例复发率为100%。结论:发病年龄、性别、过敏原阳性、Ig A升高、重症病例及1周内发现尿常规异常与HSP复发关系密切,特别是重症病例,在初诊和随访过程中应提高警惕,密切观察。
Objective: To investigate the clinical factors related to the recurrence of Henoch-Schonlein purpura (HSP) in children. Methods: The clinical data of 118 children with HSP admitted from January 2010 to December 2013 in Jiangmen Central Hospital were retrospectively analyzed. One year after follow-up, the patients were divided into non-recurrence group and recurrence group. The age of onset, Gender, prodromal infection, positive allergens, elevated IgA, severe cases, urine abnormalities found within 1 week, the onset of treatment and the incidence of purpura and other clinical indicators of differences. Results: The recurrence rate of Henoch-Schonlein purpura was 29.66% and the relapse time was within 6 months after treatment. The incidence of prodromal infection, onset of treatment and allergic purpura were not associated with recurrence (P> 0.05) Sex, allergen positive, elevated IgA, severe cases and urine abnormalities found within 1 week, the difference was statistically significant (P <0.05), of which the recurrence rate of severe cases was 100%. Conclusion: Age, gender, allergen positive, elevated IgA, severe cases and urine abnormalities found within 1 week and HSP recurrence are closely related, especially in severe cases, should be vigilant during the first visit and follow-up, close observation.