论文部分内容阅读
化学致癌物诱发肿瘤时并没有将癌基因引入恶变的细胞内。因此,这种癌变过程是化学致癌物与靶细胞中存在的基因相互作用的结果。黄曲霉毒素B,(AFB_1)可能是肝癌的主要病因之一。动物实验证实AFB。能诱发肝癌,体外细胞培养中AFB_1引起染色体畸变及姐妹染色单体互换(SCE)显著升高,且与浓度成正相关。
Chemotactic tumor-induced cancer did not introduce malignant cells into malignant cells. Therefore, this process of carcinogenesis is the result of chemical carcinogens interacting with genes present in target cells. Aflatoxin B, (AFB_1) may be one of the major causes of liver cancer. Animal experiments confirmed AFB. Induced hepatocellular carcinoma, chromosome aberration induced by AFB_1 and SCE increased significantly in vitro and positively correlated with the concentration.