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目的探讨无创正压机械通气治疗慢性阻塞性肺疾病(COPD)合并Ⅱ型呼吸衰竭的疗效。方法选择近年来收治的COPD合并Ⅱ型呼吸衰竭患者90例,随机分为治疗组和对照组,两组均给予常规抗感染、解痉平喘、祛痰、能量支持等常规治疗,对照组予低浓度氧疗,治疗组采用面罩BIPAP呼吸机治疗。观察两组患者临床症状、生命体征、血气分析变化。结果 BiPAP治疗组患者临床症状、体征和血气指标在治疗后较治疗前明显改善(P<0.05),两组治疗后的血气指标比较有统计学意义(P<0.05)。结论 BiPAP通气支持治疗COPD合并呼吸衰竭疗效显著。
Objective To investigate the curative effect of noninvasive positive pressure mechanical ventilation on chronic obstructive pulmonary disease (COPD) with type Ⅱ respiratory failure. Methods Ninety patients with COPD and type Ⅱ respiratory failure who were treated in recent years were randomly divided into treatment group and control group. Both groups were given routine anti-infective, antispasmodic and antiasthmatic, expectorant, and energy supportive measures, while those in control group were given low-dose Oxygen therapy, the treatment group with mask BIPAP ventilator treatment. Clinical symptoms, vital signs and blood gas analysis were observed in two groups. Results The clinical symptoms, signs and blood gas indexes of patients in BiPAP group were significantly improved after treatment (P <0.05). The blood gas indexes of two groups after treatment were statistically significant (P <0.05). Conclusions BiPAP ventilation is effective in treating COPD with respiratory failure.