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急性骨髓硬化是一种罕见的迅速致死性血液疾病,其特征是全血细胞减少,偶见未分化原始细胞,无泪滴状异形红细胞;骨髓弥漫性纤维化伴非典型巨核细胞增生,三系增生异常;无巨肝巨脾征。本文报告1例铁粒幼细胞性贫血2年半后转变为急性骨髓硬化。
Acute myelofibrosis is a rare, rapidly fatal hematological disorder characterized by pancytopenia and occasionally undifferentiated primitive cells without teardrop-shaped shaped erythrocytes; diffuse myelofibrosis with atypical megakaryocyte hyperplasia and three-lineage hyperplasia Abnormal; no giant spleen syndrome. This report reports a case of acute myelogenous leukemia in 2 patients after 2 years of acute micromegaly.