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目的:评价口服波生坦加用吸入性treprostinil治疗肺动脉高压(PAH)患者的安全性和有效性。背景:在波生坦治疗PAH的同时通过吸入方式加用一种长效前列环素类似物可能是使治疗达到最佳化的安全有效的策略。
OBJECTIVE: To evaluate the safety and efficacy of oral bosentan plus inhaled treprostinil in patients with pulmonary hypertension (PAH). BACKGROUND: The addition of a long-acting prostacyclin analogue to bosentan in the treatment of PAH may be a safe and effective strategy for optimal treatment.