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目的探讨药物流产周期中BBT的变化及米非司酮对卵巢功能的影响。方法嘱药物流产妇女自服药日起每日清晨醒后立即测口温5min,将结果记录在基础体温单上,连续测量至转经并月经干净后复诊,制成BBT曲线。结果146例有可分析的BBT结果(完全流产145例,药流失败1例,无不全流产的BBT结果)。BBT双相137例占94.5%;BBT单相8例,占5.5%;89.0%药流妇女BBT于服米索前列醇当日及孕囊排出后第1天开始下降;94.5%BBT降幅在0.2℃~0.5℃;80.7%的BBT于孕囊排出后至7d内降至最低值;95.9%BBT最大降幅在0.3℃~0.7℃;BBT双相者平均排卵日为20.8±0.3d,黄体期为12.5±0.2d。多数表现为黄体期缺陷。经多元相关分析发现,宫腔操作史、药流史、BBT变化各指标及出血时间长短之间均无相关性。结论药流BBT多于服米索前列醇当日或胎囊排出后第1天开始下降,降幅0.2℃~0.5℃,约经1周BBT逐渐下降达最低水平,最大降幅为0.3℃~0.7℃,于20d左右BBT上升排卵。黄体期维持12d左右,多存在一定程度的黄体期缺陷,但对转经、经期和经量无影响。BBT尚可监测药流失败和再次妊娠。
Objective To investigate the changes of BBT during abortion and the effect of mifepristone on ovarian function. The method of ordering abortion women since the morning after taking medicine daily wake up immediately measured mouth temperature 5min, the results recorded in the basal body temperature on a single continuous measurement to transfer and menstruation clean after the referral, made BBT curve. Results 146 cases had BBT results (145 cases of complete abortion, 1 case of failed medical abortion, and no BBT results of incomplete abortion). BBT biphasic 137 cases accounted for 94.5%; BBT single-phase 8 cases, accounting for 5.5%; 89.0% of drug abortion women BBT on the first day after taking misoprostol and gestational sac began to decline; 94.5% BBT decline in 0.2 ℃ ~ 0.5 ℃; the BBT of 80.7% decreased to the lowest within 7 days after the discharge of gestational sac; the maximum decrease of 95.9% BBT was between 0.3 ℃ and 0.7 ℃; the average ovulation day of BBT biphasic was 20.8 ± 0.3d and the luteal phase was 12.5 ± 0.2d. The performance of the majority of luteal defects. Multivariate analysis showed no correlation between the history of uterine cavity operation, the history of medical abortion, the changes of BBT and the time of bleeding. Conclusions The BBT of drug flow is more than that of misoprostol on day 1 or day 1 of fetal capsule discharge, decreasing by 0.2 ℃ ~ 0.5 ℃. BBT gradually drops to the lowest after about 1 week, with the maximum decrease of 0.3 ℃ ~ 0.7 ℃ BBT around 20d rise ovulation. Luteal phase to maintain about 12d, there is a certain degree of luteal phase defects, but on the turn, menstrual and the amount of no effect. BBT can still monitor the failure of medical abortion and pregnancy again.