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目的:研究分析使用阿米替林联合唑来膦酸治疗肺癌转移性骨痛的疗效。方法:以66例肺癌转移性骨痛患者为研究对象;将患者随机分为两组,对照组给予唑来膦酸治疗,实验组患者联合使用阿米替林和唑来膦酸,观察对比两组患者的治疗效果。结果:实验组患者疼痛评分低于对照组患者,P<0.05;实验组患者焦虑抑郁状态低于对照组患者,P<0.05。结论:采用阿米替林联合唑来膦酸治疗肺癌转移性骨痛患者具有较好的效果,值得在临床应用。
OBJECTIVE: To study the efficacy of amitriptyline plus zoledronic acid in the treatment of metastatic bone cancer of lung cancer. Methods: Sixty-six patients with metastatic bone cancer of lung cancer were selected as study subjects. Patients were randomly divided into two groups. Patients in the control group were treated with zoledronic acid. Patients in the experimental group were treated with amitriptyline and zoledronic acid. Group of patients treatment effect. Results: The score of pain in the experimental group was lower than that of the control group (P <0.05). The anxiety and depression status of the experimental group was lower than that of the control group (P <0.05). Conclusion: Amitriptyline combined with zoledronic acid in the treatment of metastatic bone cancer patients with lung cancer has a good effect, it is worth in clinical application.