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目的探讨心肌缺血预适应在急性心肌梗塞中的临床意义。方法５８例ＡＭＩ患者分为梗塞前２４ｈ内有心绞痛组３５例，梗塞前２４ｈ内无心绞痛组２３例。入院后按统一方案治疗，观察比较两组的心肌酶峰值、严重心律失常发生率及院内死亡率。结果有梗塞前心绞痛组心肌酶峰值、严重心律失常发生率及院内死亡率显著低于无梗塞前心绞痛组（Ｐ＜００５）。结论梗塞前有心绞痛发作能有效的诱导缺血预适应，对心肌起保护作用，使心肌梗塞面积缩小，心律失常发生率及死亡率降低。
Objective To investigate the clinical significance of myocardial ischemic preconditioning in acute myocardial infarction. Methods Fifty-eight AMI patients were divided into angina pectoris group (n = 35) within 24 hours before infarction and no angina pectoris group (n = 23) within 24 hours before infarction. After admission according to a unified program of treatment, observed and compared the two groups of myocardial enzyme peak, severe arrhythmia and hospital mortality. The results showed that the myocardial enzymes peaked before angina pectoris group, the incidence of serious arrhythmia and in-hospital mortality were significantly lower than those before angina pectoris group (P <005). Conclusions The onset of angina pectoris before infarction can effectively induce ischemic preconditioning, which can protect myocardium, reduce the area of myocardial infarction, and reduce the incidence of arrhythmia and mortality.