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Vero细胞分析法常用于测定人血清中白喉抗毒素的保护水平或通过测定免疫小鼠血清产生的白喉抗毒素滴度来估价菌苗中白喉类毒素的效价。Vero细胞在培养液中的代谢活动和存活数能被白喉毒素所抑制。这种抑制又能被血清中的白喉抗毒素中和。试验时
Vero cell assays are commonly used to determine the level of protection against diphtheria anti-toxin in human serum or to assess the titer of diphtheria toxoid in the vaccine by measuring the diphtheria antitoxin titer produced in the serum of immunized mice. The metabolic activity and viability of Vero cells in culture fluid can be inhibited by diphtheria toxin. This inhibition in turn can be neutralized by diphtheria antitoxin in serum. Test time