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建立了GC/MS同时测定尿中吗啡和可待因含量的分析方法。线性范围为20—1000ng/ml(r=0.9997);方法回收率是:吗啡86.8±7.9%,可待因84.7±7.0%。天内测定RSD<10%,天间测定RSD<15%。该法已用于生物样品中吗啡和可待因的测定。
An analytical method for simultaneous determination of morphine and codeine in urine by GC / MS was established. The linear range was 20-1000 ng / ml (r = 0.9997). The recoveries were 86.8 ± 7.9% for morphine and 84.7 ± 7.0% for codeine. RSD <10% for days and RSD <15% for days. This method has been used for the determination of morphine and codeine in biological samples.