帕罗西汀（paroxetine）是一种选择性5-HT受体抑制剂，目前用作抗抑郁药，可用气-液色谱或HPLC荧光检测进行体液分析。本文报道的HPLC－UV法比上述两法更快速，且对重复剂量的研究有足够的灵敏度。仪器HPLC系统，655A－12型高压泵，Kratos783型可变波长UV检测器，WISP712型自动 Paroxetine, a selective 5-HT receptor inhibitor, is currently used as an antidepressant for body fluid analysis using gas-liquid chromatography or HPLC fluorescence detection. HPLC-UV method reported in this article is faster than the above two methods, and sufficient sensitivity for repeated dose studies. Instrument HPLC System, Model 655A-12 High Pressure Pump, Kratos Model 783 Variable Wavelength UV Detector, Model WISP712 Automatic