肾病综合征(NS)常处于高凝状态,易并发血栓形成,严重影响治疗效果及预后。既往用普通肝素或维生素K拮抗剂等抗凝剂防治NS并发血栓形成,因易出血或效果欠佳而受到限制。低分子肝素(Low mo—lecular weight heparin, LMWH.速避凝)是经普通肝素化学或酶促解聚后产生的一种新型抗凝剂,具有生物利用度高、半衰期长、量效关系明确、副作用少、使用方便等优点,近年有逐渐取代普通肝素的趋势。我们从1999年3月至2000年3月对14例原发性NS高凝 Nephrotic syndrome (NS) often hypercoagulable state, easily complicated by thrombosis, seriously affecting the treatment and prognosis. In the past with unfractionated heparin or vitamin K antagonist anticoagulants such as prevention and treatment of concurrent thrombosis, due to bleeding or ineffective and limited. Low molecular weight heparin (LMWH) is a new anticoagulant produced by chemical or enzymatic depolymerization of unfractionated heparin. It has the advantages of high bioavailability, long half-life and clear dose-effect relationship , Less side effects, ease of use and other advantages, in recent years have gradually replaced the trend of unfractionated heparin. We from March 1999 to March 2000 on 14 cases of primary NS hypercoagulability