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本文报道三例慢性粒细胞白血病的少见Ph易位:例1为遮蔽的Ph染色体,由于t(2;9;22)(p23;q34;q11)所致;例2为t(11;22)变异易位;例3为t(3;14;22)复杂变异易位。对其临床表现及生物学意义作了简要讨论。
We report the rare Ph translocation in three cases of chronic myeloid leukemia: case 1 is a shaded Ph chromosome due to t (2; 9; 22) (p23; q34; q11); case 2 is t (11; 22) Variant translocation; Example 3 is the complex variant translocation of t (3; 14; 22). The clinical manifestations and biological significance of a brief discussion.