病例介绍患者1,女,58岁。2015年1月15日以“右膝重度骨关节炎”收入院。术前双下肢静脉彩色多普勒超声(彩超)、心脏功能、凝血功能检查均无异常。未行双下肢动脉彩超。无高血压病史。于2015年1月21日在全身麻醉(全麻)下行右全膝关节置换术,手术时间约90 min。术后给予预防感染、抗凝等治疗。2015年1月23日,患者伤口出现渗血,小腿瘀斑,凝血酶原时间15.2 s, Case description Patient 1, female, 58 years old. January 15, 2015 to “right knee severe osteoarthritis” income hospital. Preoperative double lower extremity venous color Doppler ultrasound (color Doppler ultrasound), cardiac function, coagulation tests were no abnormalities. No lower extremity arterial ultrasound. No history of hypertension. On January 21, 2015, under total knee arthroplasty under general anesthesia (general anesthesia), the operation time was about 90 min. Postoperative infection prevention, anticoagulation and other treatment. January 23, 2015, patients with bleeding wounds, calf ecchymosis, prothrombin time 15.2 s,