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目的:研究长期服用小剂量复方磺胺甲噁唑(compound sulfamethoxazole tablets,SMZCo)对预防Ⅱ型慢性细菌性前列腺炎复发患者的临床疗效。方法:选取2012年1月—2014年1月期间接受治疗的Ⅱ型慢性细菌性前列腺炎患者108例,采用随机数表法将其分为观察组(n=54)和对照组(n=54),对照组患者给予口服前列康片治疗,观察组患者在口服前列康的同时口服小剂量SMZCo片治疗,对比两组患者治疗后的疗效和治愈复发率。结果:观察组患者的总有效率94.44%显著高于对照组83.32%(P<0.05),其随访复发率16.12%显著低于对照组40.00%(P<0.05)。结论:长期服用小剂量SMZCo片能提高Ⅱ型慢性细菌性前列腺炎患者的临床疗效,降低Ⅱ型慢性细菌性前列腺炎的复发率。
Objective: To study the long-term use of small doses of compound sulfamethoxazole (compound sulfamethoxazole tablets, SMZCo) in the prevention of type Ⅱ chronic bacterial prostatitis recurrence in patients with clinical efficacy. Methods: A total of 108 patients with type Ⅱ chronic bacterial prostatitis who were treated between January 2012 and January 2014 were selected and divided into observation group (n = 54) and control group (n = 54) by random number table ). The patients in the control group were treated with Qianliekang tablets. The patients in the observation group were treated with oral administration of Qianliekang while taking small doses of SMZCo tablets. The curative effect and recurrence rate were compared between the two groups. Results: The total effective rate in the observation group was 94.44%, significantly higher than that in the control group (83.32%, P <0.05). The follow-up recurrence rate was significantly lower than that in the control group (16.12% vs 40.00%, P <0.05). Conclusion: Long-term use of small doses of SMZCo tablets can improve the clinical efficacy of type Ⅱ chronic bacterial prostatitis and reduce the recurrence rate of type Ⅱ chronic bacterial prostatitis.