本文对505例慢性胆囊炎的肝脏损害进行了观察,结果显示肝肿大15.45％,胆汁性肝硬化5.15％,血清胆红素异常36.07％,白蛋白降低42.35％、ALT升高42.36％,ALT升高呈—过性,可反复出现,且有发生急消失快的特点。38例进行肝活检,其中肝细胞浊肿变性92.1％、肝小叶及门管区慢性炎性细胞浸润89.5％、肝结节增生13.2％、肝细胞坏死 5.3％、胆汁淤积、脂肪变和肝窦扩张2.6％,本文资料表明慢性胆囊炎,尤其是反复急性发作者,常有不同程度的肝脏受累。 505 cases of chronic cholecystitis liver damage were observed, the results showed hepatomegaly 15.45%, biliary cirrhosis 5.15%, abnormal serum bilirubin 36.07%, 42.35% reduction of albumin, ALT increased 42.36%, ALT Elevated was - transient, can be repeated, and the rapid disappearance of emergency features. Thirty-eight patients underwent liver biopsy, including 92.1% of hepatocellular degeneration, 89.5% of chronic inflammatory cell infiltration in hepatic lobule and portal tract, 13.2% of hepatic nodular hyperplasia, 5.3% of hepatocellular necrosis, cholestasis, steatosis and sinusoidal dilatation 2.6%, this data show that chronic cholecystitis, especially repeated acute onset, often varying degrees of liver involvement.