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目的观察逍遥丸联合布拉氏酵母菌治疗儿童肠易激综合征(IBS)临床疗效及安全性。方法 67例IBS患儿按随机数字表法分为观察组(n=35)和对照组(n=32)。对两组患儿均进行心理暗示和辅导,并加强饮食管理。对照组采用逍遥丸3.5~6岁每次4丸,6~14岁每次6丸,bid口服。观察组在对照组基础上联合布拉氏酵母菌0.25g/次,bid饭后口服。两组均2周为一疗程。结果观察组患儿痊愈率为62.86%,与对照组的31.25%比较,差异有统计学意义(P<0.01);观察组患儿治愈率为91.42%,与对照组的68.75%比较,差异有统计学意义(P<0.05)。治疗后两组患儿中医症候评分均比治疗前明显降低(P<0.01),但观察组更明显,治疗后观察组与对照组比较,差异有统计学意义(P<0.01)。结论逍遥丸联合布拉氏酵母菌治疗儿童IBS临床疗效明显。如果能够配合心理治疗临床效果会更好。
Objective To observe the clinical efficacy and safety of Xiaoyao Pill combined with B. Cerevisiae in the treatment of children with irritable bowel syndrome (IBS). Methods 67 cases of IBS children were divided into observation group (n = 35) and control group (n = 32) by random number table method. Psychological suggestion and counseling to both groups of children and diet management. The control group adopted Xiaoyao Pill 3.5 ~ 6 years old each 4 pills, 6 ~ 14 years old each 6 pills, bid oral. Observation group in the control group based on the combination of Brachyerella 0.25g / times, after oral administration of rice. Two groups were 2 weeks for a course of treatment. Results The cure rate in the observation group was 62.86%, which was significantly different from that in the control group (31.25%, P <0.01). The cure rate in the observation group was 91.42%, compared with 68.75% in the control group Statistical significance (P <0.05). The TCM symptom scores of both groups were significantly lower than those before treatment (P <0.01), but the observation group was more obvious. The difference between the observation group and the control group after treatment was statistically significant (P <0.01). Conclusion Xiaoyao Pill combined with B. Cerevisiae in children with clinical efficacy of IBS significantly. If you can cope with clinical psychotherapy will be better.