系统性红斑狼疮(Systemic Lupus Erythematosus SLE)是以皮肤、关节、肾、浆膜、心、肺、中枢神经等多脏器受累的反复活动与缓解的炎症性疾病。从临床角度分析归属风湿性疾病,从病理学角度属结缔组织病(旧称胶原病),从病因论属自身免疫病。 一、分类 近年由于分子生物学手段研究的深入,SLE不仅可有多种不同类型的临床表现,而且抗核抗体类型也有很大差异。因此有必要对SLE进行详细分类研究。就起病形式看多是慢性、亚急性的,但 Systemic Lupus Erythematosus (SLE) is an inflammatory disease that involves repeated activities and remissions of multiple organs such as the skin, joints, kidneys, serosa, heart, lungs and central nervous system. From the clinical point of view attribution of rheumatic diseases, from the perspective of pathology is connective tissue disease (formerly known as collagen disease), from the etiology is an autoimmune disease. First, the classification In recent years, due to the depth of molecular biology research, SLE can not only have a variety of different types of clinical manifestations, and anti-nuclear antibody types are also very different. Therefore it is necessary to conduct a detailed classification study of SLE. On the form of onset is mostly chronic, subacute, however