原发性十二指肠腺癌较少见,多位于十二指肠降部中段,球部腺癌更罕见,临床无特征性表现,诊断较困难。我们综合三个单位发现的原发性十二指肠腺癌7例(不包括壶腹癌),其中球部2例,降部中段5例。4例行十二指肠胰胃部分切除术,术后随访2例三年健在。 Primary duodenal adenocarcinoma is rare, mostly in the middle part of the descending part of the duodenum. Adenocarcinoma of the bulbar gland is more rare and clinically uncharacteristic. Diagnosis is difficult. We found that there were 7 primary duodenal adenocarcinomas (excluding ampullary carcinoma) found in three units, of which 2 were in the bulb and 5 in the middle of the descending segment. Four patients underwent partial duodenal pancreatic resection. Two patients were followed up for three years.