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目的探讨玻璃体切割术联合玻璃体腔注药治疗化脓性眼内炎的临床疗效。方法收集化脓性眼内炎18例(18只眼),其中16只眼进行了玻璃体切除术联合玻璃体腔注药,2只眼单纯应用抗生素、皮质类固醇激素进行眼局部及全身的用药治疗,术后随访1~6个月。结果行玻璃体切割术联合玻璃体腔注药的16只眼中,13只眼矫正视力有不同程度提高(81.25%),1只眼(6.25%)视力没改变,2只眼(12.5%)视力降低;其中视力>0.5者2只眼,视力在0.1~0.5者5只眼,视力<0.1者6只眼,眼前数指2只眼,无光感1只眼。单纯应用药物治疗的2只眼因炎症反应较重,导致视力丧失,眼球萎缩。结论对于化脓性眼内炎,玻璃体切割术联合玻璃体腔注药的治疗效果明显优于单纯应用药物治疗,早期诊断、及时治疗是挽救眼球和视功能的关键。
Objective To investigate the clinical efficacy of vitrectomy combined with vitreous cavity injection in the treatment of suppurative endophthalmitis. Methods Eighteen eyes (18 eyes) with purulent endophthalmitis were collected. Vitrectomy and vitreous cavity injection were performed in 16 eyes. Local and systemic drug therapy was given in 2 eyes with antibiotics and corticosteroids alone. Follow-up 1 ~ 6 months. Results Among the 16 eyes treated with vitrectomy combined with intravitreal injection, the corrected visual acuity was improved to 81.25% in 13 eyes, unchanged in 1 eyes (6.25%), and decreased in 2 eyes (12.5%). Including visual acuity> 0.5 in 2 eyes, visual acuity in 0.1 to 0.5 in 5 eyes, visual acuity <0.1 in 6 eyes, the number of eyes refers to 2 eyes, no light perception in 1 eye. Simple application of drug treatment of the two eyes due to severe inflammatory reactions, resulting in loss of vision, eye atrophy. Conclusion For suppurative endophthalmitis, vitrectomy combined with intravitreal injection is superior to drug therapy alone. Early diagnosis and prompt treatment are the keys to salvage the eye and visual function.