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目的通过对比,探讨山莨菪碱在急性腹泻病治疗中所起的作用。方法在急诊和肠道门诊就诊的241例急性腹泻病患者,采用抽签的方式随机分为治疗组(145例)和对照组(96例)。在常规补液等治疗的基础上,治疗组给予山莨菪碱静脉滴注,对照组给予相同液体不加山莨菪碱。观察2组患者腹泻症状、次数等的变化。结果治疗组显效率(73.8%vs43.7%)及总有效率(97.9%vs83.3%)明显高于对照组(P均<0.01)。结论山莨菪碱在急性腹泻病治疗中能有效减轻症状,缓解病情且价格低廉。
Objective To compare the role of anisodamine in the treatment of acute diarrhea. Methods A total of 241 acute diarrhea patients treated in the emergency and intestine clinics were randomly divided into treatment group (n = 145) and control group (n = 96) by random sampling. On the basis of conventional rehydration therapy, the treatment group was treated with intravenous anisodamine, and the control group was given the same liquid without anisodamine. The changes of diarrhea symptoms, frequency and so on in 2 groups were observed. Results The markedly effective rate (73.8% vs 43.7%) and total effective rate (97.9% vs 83.3%) in the treatment group were significantly higher than those in the control group (all P <0.01). Conclusions Anisodamine can relieve the symptoms and relieve the condition effectively at low cost in the treatment of acute diarrhea.