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近年来,冠状动脉微血管疾病的临床意义日益受到人们的高度重视.2013年,ESC稳定性冠状动脉疾病治疗指南中正式将此病列入冠心病的临床类型,并提出了初步的诊断和治疗建议.迄今为止,国际上尚无专门针对冠状动脉微血管疾病的指南或共识,对于此病的病因、发病机制、临床分型、诊断、治疗和预后等诸方面的认识仍有很多误区,未来冠心病治疗的突破,取决于对于冠状动脉微血管病变的理解和干预.“,”The issues concerning coronary microvascular disfunction have been extensively followed in recent years.In 2013,the related diseases were formally classified as one type of coronary heart disease by ESC stable coronary heart disease guideline and simultaneously brought forward its primary diagnosis along with treatment suggestions.So far,unfortunately,no guidelines nor consensus recognized internationally could be obtained from the coronary microvascular diseases.The genesis,pathogeny,clinical classification, diagnosis,treatments together with its prognosis are unforeseen and still remain some misunderstandings.Hence,future breakthroughs relating to the treatments of coronary heart disease will be largely hinge on our understandings as well as interventions we make to the coronary microvascular disease.