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目的:观察脉络膜黑色素瘤的临床病理特点及其与预后的关系。方法:对26例脉络膜黑色素瘤进行多种影像检查和病理学检查。结果:20例B超示眼球内实质性不均质占位;16例眼底荧光血管造影(FFA)示肿瘤内斑驳状荧光、肿瘤自身血管和视网膜毛细血管扩张等特征性改变;12例CT扫描示眼球内高密度块状影像;1例MRI示T1加权呈高信号,T2加权呈低信号;26例均为病理学检查证实。随访5例,2例死于肝转移,3例存活。结论:FAA、MRI等检查对该病具有一定的诊断价值,但必须综合多种检查结果作出临床诊断。该病的预后与瘤细胞类型、分化程度以及肿瘤的大小等因素有关。
Objective: To observe the clinicopathological features of choroidal melanoma and its relationship with prognosis. Methods: Twenty-six cases of choroidal melanoma underwent multiple imaging examinations and pathological examinations. RESULTS: Twenty cases of B-mode ultrasonography showed substantial heterogeneity in the eyeballs; 16 cases of fundus fluorescein angiography (FFA) showed characteristic changes of tuft-like fluorescence, tumor’s own blood vessel, and retinal capillary dilation; 12 cases of CT scan High-density block images of the eyeballs were shown; 1 case of MRI showed T1 weighted high signal, T2 weighted low signal; 26 cases were confirmed by pathological examination. Five patients were followed up, 2 died of hepatic metastases, and 3 survived. Conclusion: FAA, MRI, etc. have certain diagnostic value for this disease, but a variety of test results must be combined to make a clinical diagnosis. The prognosis of the disease is related to the type of tumor cells, the degree of differentiation, and the size of the tumor.