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目的 探讨急性冠脉综合征患者入院时降钙素原水平对并发心源性休克的预测价值.方法 选择2014年10月-2016年5月在广州市增城区人民医院心内科病房就诊的795例急性冠脉综合征患者为研究对象,其中急性ST段抬高心梗合并心源性休克65例(A组),无并发症的急性ST段抬高心梗320例(B组),非ST段抬高急性冠脉综合征410例(C组).收集3组患者的临床资料并进行血液生化指标检测.结果 与后两组(B组&C组)患者对比,急性ST段抬高心梗合并心源性休克组患者入院的降钙素原水平明显升高,差异有统计学意义(P＜0.001).多元线性逐步回归分析显示,降钙素原与心源性休克独立相关(P =0.006),且心源性休克患者中降钙素原与C-反应蛋白之间无相关性(R=0.03,P=0.78).结论 急性冠脉综合征患者入院检测降钙素原水平升高,对预测住院期间发生心源性休克可能具有一定价值.“,”Objective To investigate the prognostic value of procalcitonin (PCT) in acute coronary syndrome (ACS) complicated with cardiogenic shock (CS).Methods 795 ACS patients with the clinical manifestations were selected by systematic sampling combined with simple random sampling were categorized into 3 different groups according to their specific conditions:Group A (n=65) with acute ST segment-elevation myocardial infarction (STEMI),Group B (n=320) with STEMI but without complications such as heart failure,malignant ventricular arrhythmias requiring electric cardioversion,and Group C (n=410) with non-ST segment-elevation acute coronary syndrome (NSTEACS).Peripheral venous blood samples were collected at admission to test the plasma levels of procalcitonin (PCT) and C-reactive protein (CRP).Next morning peripheral venous blood samples were collected to exmiane the liver function,fasting blood-glucose (FPG),high-density lipoprotein cholesterol (HDL-C),low-density lipoprotein cholesterol (LDL-C),triglyceride (TG),uric acid (UA),etc.Ultrasonic echocardiography was conducted within 48b after admission to test the left ventricular ejection fraction (LVEF).Multiple linear stepwise regression analysis was used to analyze the correlations among different factors.Results The diabetes prevalence rate,PCT level,and CPR level of Group A were all significantly higher than those of Groups B and C (all P ＜0.05),and the LVEF prevalence rate of Group A was significantly lower than those of Groups B and C (both P ＜0.05).Multiple linear stepwise regression analysis revealed an independent positive association between PCT and CS (P=0.006),and no correlations were found in CS patients between CRP and PCT values (R=0.03,P =0.78).Conclusion Increased PCT level has some predictive value in the occurrence of cardiogenic shock.